Active ingredient

  • Inactivated bovine rotavirus G6 strain TM-91 
  • Inactivated bovine coronavirus strain C-197 
  • Adhesion F5 (K99) from Escherichia coli strain ECI17

 

Indications

Active immunisation of healthy pregnant cows and heifers to provide calves with passive immunity targeted at reducing mortality, incidence and severity of diarrhoea from gastrointestinal infections caused by enteropathogenic Escherichia coli, Bovine rotavirus and coronavirus.

 

Onset of immunity: Passive immunity in calves starts with colostrum feeding.

 

Dosage and administration

Route:

  • Subcutaneously or Intramuscularly in the anterior third of the neck
  • Avoid inadvertent intravascular administration

 

The product is for use in cows in the last trimester of pregnancy.

 

Unvaccinated cows:
3mL vaccination 5-12 weeks prior to calving with revaccination 3 weeks after the first vaccination

 

Vaccinated cows:
3mL vaccination during pregnancy 3-12 weeks prior to calving

 

  • Common aseptic procedures should be used during vaccination
  • Use only sterile syringes and needles.
  • Allow the vaccine to come to 18 to 22 °C before use.
  • Shake well before and occasionally during administration.

 

Protection of calves depends on the presence of colostral antibodies (obtained from vaccinated cows) in the gut during the first weeks of life until the individual immune status of the calves is formed. An adequate intake of colostrum throughout first 2-3 weeks of life is required for maximum efficacy from vaccination. All calves must be supplied with sufficient amount of colostrum up to six hours after calving. The peak titre of antibodies in the colostrum occurs between 0 and 24 hours after parturition. In herds with unfavourable epizootological situations, collecting the colostrum of vaccinated mothers from the first 6 - 8 milkings is recommended. During the first two weeks of life the calves must be fed with 2.5 - 3 litres per day.

To reach the maximum decrease of morbidity and reduction of intensity of diarrhoea it is necessary to assure that the whole herd undergoes the vaccination treatment and all newborn calves must be fed with the antibody enhanced colostrum.

 

Pharmacodynamic Properties

Inactivated oil vaccine is prepared from chemically inactivated virus antigens derived from bovine rotavirus G6 strain TM-91 and bovine coronavirus strain C-197 propagated in the established cell cultures, and from adhesin F5 (K99) of Escherichia coli propagated in the liquid growth medium. The vaccine is designed for stimulation of the active immunity of pregnant cows against these antigens, which is transferable to calves by colostrum / milk during milk feeding.

 

Contraindications

Do not vaccinate animals ill or suspected of any disease.

 

Incompatibilities

Do not mix with any other vaccine or immunological product.

 

Adverse reactions (frequency and seriousness)
Occasionally a slight swelling up to 2 cm in diameter may be observed at the site of injection. It will reabsorb within 14 days of injection. If intravascular injection occurs, cerebral or cardiac embolism may occur resulting in staggering or even death.

 

Use during pregnancy
This product is designated for the use in cows in the last trimester of pregnancy.

 

Interaction with other medicinal products and other forms of interaction
No information is available on the safety and efficacy from the concurrent use of this vaccine with any other.

 

Overdose (symptoms, emergency procedures, antidotes), if necessary
Administration of a double dose can occasionally cause a slightly extended swelling.

 

Withholding periods

Milk: Nil 
Meat: Nil

 

Handling Precautions
May be harmful if swallowed. Repeated exposure may cause skin allergy.
Handle the product with care to avoid oral exposure. Avoid skin contact.

 

First Aid
If swallowed do NOT induce vomiting. For advice contact the National Poisons Centre 0800 POISON (0800 764 766) or a doctor immediately.

 

Disposal
Preferably dispose of product by use. Otherwise dispose of product, packaging and waste at an approved landfill or equivalent facility.

 

Other

Store between 2-8 °C, protected from light. Do not freeze. 

Unbroached three years life to expiry

Once vial is broached, use contents within 10 days or discard.

 

Registered pursuant to the ACVM Act 1997, No. A10777

See www.foodsafety.govt.nz for registration conditions

 

Safety Data Sheet available upon request

Rotagal

  • The vaccine against Rotavirus scours… with significant cost advantages!
     

    Rotagal vaccine is an aid in the prevention of calf scours caused by Bovine rotavirus, coronavirus, and E.coli.
     

    Available only under veterinary authorisation

     

    Pack sizes

    90 mL and 450 mL

Contact

09-476 7391

©2019 by Phoenix Pharm Distributors Ltd